Drug Standards
eMolecules 20559-55-1 | Medchem Express | Oxibendazole | 50mg | 446272455 | HY-B0299 | MFCD00847838 | 249.27 | C12H15N3O3
ChemScene | 5-Bromo-2-methoxyphenol | 5g | 789369655 | CS-W007658 | 37942-01-1 | MFCD00673137 | 203.035 | C7H7BrO2
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Selleck Chemical LLC Lidocaine hydrochloride S4667-100mg
Lidocaine hydrochloride (Lidothesin Lignocaine Xyloneural) is an inhibitor of epidermal growth factor receptor (EGFR) and has antiproliferative effect on human tongue cancer cells Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent
Medchemexpress LLC Febantel | 58306-30-2 | 99.9% | 446.48 | 1 G
Febantel is an oral dewormer used to treat gastrointestinal nematodes in sheep, as well as roundworm and tapeworm infections in poultry and livestock. It also inhibits the embryonic development of mouse hairworms and whipworm eggs.
- Acts as an oral dewormer
- Inhibits embryonic development of certain parasites
- Suitable for research use only
Medchemexpress LLC Rosuvastatin sodium | 147098-18-8 | 99.9% | 503.52 | 1 ML
Rosuvastatin Sodium is a potent and selective competitive inhibitor of HMG-CoA reductase (HMGCR) with an IC50 of 11 nM. It also potently blocks hERG current with an IC50 of 195 nM. This compound reduces the expression of mature hERG and its interaction with heat shock protein 70 (Hsp70), contributing to its biological activity. Rosuvastatin Sodium is effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. It is intended for research use only.
- Competitive HMG-CoA reductase (HMGCR) inhibitor
- Potently blocks hERG current
- Reduces expression of mature hERG protein
- Lowers LDL cholesterol and triglycerides
- Reduces C-reactive protein levels
Medchemexpress LLC STAT3-D11-PROTAC-VHL | 96.3% | 1 MG
This PROTAC degrader targets Signal Transducer and Activator of Transcription 3 (STAT3). It exhibits anti-tumor activity with IC50 values of 1335 nM and 1973 nM against HeLa and MCF-7 cells, respectively. The compound binds to the DNA-binding domain of STAT3, recruits the E3 ligase VHL to form a ternary complex, leading to ubiquitination and subsequent degradation by the proteasome. It also inhibits tumor cell growth, induces cell cycle arrest and apoptosis, and suppresses tumor immune evasion.
- Degrades STAT3 transcription factor.
- Exhibits anti-tumor activity in HeLa and MCF-7 cells.
- Recruits E3 ligase VHL for STAT3 degradation.
- Inhibits tumor cell growth.
- Induces cell cycle arrest and apoptosis.
- Suppresses tumor immune evasion.
Sigma Aldrich Fine Chemicals Biosciences Artesunate United States Pharmacopeia (USP) Reference Standard | 88495-63-0 | 200MG
Artesunate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 384.42 | 88495-63-0 | 200MG
Medchemexpress LLC Seco-DUBA | 1227961-59-2 | 98.1% | 526.97 | 1 MG
Seco-DUBA is a duocarmycin (DUBA) prodrug that contains two hydroxyl groups, each capable of coupling to an antibody via a linker. It is primarily used in the synthesis of antibody-drug conjugates (ADCs). Research indicates that Seco-DUBA dose-dependently reduces cell viability, demonstrating potency and efficacy comparable to DUBA in SK-BR-3 cells. It also induces high sensitivity in SK-BR-3, SK-OV-3, and SW620 cell lines. In vivo studies suggest that Seco-DUBA is likely converted to DUBA almost instantaneously.
- Contains two hydroxyl groups for antibody coupling via a linker
- Used in the synthesis of antibody-drug conjugates (ADCs)
- Dose-dependently reduces cell viability
- Potent and efficacious as DUBA in SK-BR-3 cells
- Causes high sensitivity in SK-BR-3, SK-OV-3, and SW620 cells
- Likely converts to DUBA almost instantaneously in vivo
Sigma Aldrich Fine Chemicals Biosciences Budesonide European Pharma
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. for further information and support please go to the website of the issuing Pharmacopoeia.
Sigma Aldrich Fine Chemicals Biosciences Flurbiprofen impurity A European Pharmacopoeia (EP) Reference Standard | 6341-72-6 |
Flurbiprofen impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 226.27 | 6341-72-6 |
Sigma Aldrich Fine Chemicals Biosciences Ethosuximide impurity A European Pharmacopoeia (EP) Reference Standard | 631-31-2 |
Ethosuximide impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 160.17 | 631-31-2 |
Sigma Aldrich Fine Chemicals Biosciences Bosentan Related Compound E United States Pharmacopeia (USP) Reference Standard | 6292-59-7 | 15MG
Bosentan Related Compound E United States Pharmacopeia (USP) Reference Standard | Mol Wt: 213.3 | 6292-59-7 | 15MG
Medchemexpress LLC 5-Aza-7-deazaguanine | 67410-64-4 | 99.9% | 151.13 | 10 MG
5-Aza-7-deazaguanine is a chemical compound that acts as a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant. It is utilized in the synthesis of base-modified nucleosides and is intended for research use only.
- Acts as a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant
- Used in the synthesis of base-modified nucleosides
- Off-white to light yellow solid appearance
- Related to oligonucleotides, nucleoside analogs, and guanosine
- Involved in research concerning cancer, cancer targeted therapy, cancer metabolism and metastasis, cell cycle/DNA damage
- Targets purine nucleoside phosphorylase and nucleoside antimetabolite/analog pathways